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The tenth batch of national procurement officially opened, and the number of enterprises and varieties involved reached a record high. The tenth batch of centralized drug procurement organized by the state officially accepted the application materials of enterprises at 8: 00 this morning at No.398 Zhanyuan Road, Nanqiao New Town, Fengxian District, Shanghai. This centralized procurement involved 62 varieties and 263 product specifications, and the number of enterprises and varieties involved reached a record high. Among them, 33 enterprises competed for nine short-listed oral sustained-release formulations of sitagliptin. There are also a number of varieties that are billions in the market of public hospitals, such as doxorubicin hydrochloride liposome injection, cefoperazone injection, piperacillin injection, compound α -ketoacid oral sustained-release dosage form, norepinephrine injection and aspirin oral sustained-release dosage form. The sales scale in sample hospitals last year all exceeded 2 billion yuan. Hengrui Pharma, Kelun Pharmaceutical, Unacon and Zhengda Tianqing participated with many varieties. Note: According to the tenth batch of national adoption documents released before, the tenth batch of national adoption rules have changed a lot, such as canceling the protection mechanism of 50% price reduction and increasing the fuse recovery mechanism by 1.8 times, and the number of B-certified enterprises affects the number of final finalists.In the first 11 months of the North Stock Exchange, the issuance scale of new shares decreased by nearly 770% year-on-year, and the new shares rose by over 100% on the first day. Statistics show that from January to November, 2024, there were 20 new shares listed on the North Stock Exchange, and the total amount of funds raised was about 4.175 billion yuan, down by nearly 70% year-on-year. The scale of new shares is generally small, and the number of new shares raised less than 200 million yuan accounts for 65% of the total number of new shares. The share price of 70% new shares rose over 100% on the first day of listing. Among them, the share price of Tongguan Mining Construction rose by 731.41% on the first day of listing, and the share prices of Shengye Electric, Keli and Wanyuantong rose by over 300% on the first day. In terms of underwriters, in the first November of 2024, the number of projects underwritten by CITIC Jiantou Securities was the highest, with a total project scale of about 699 million yuan, followed by First Venture Securities and Minsheng Securities. (Xinhua Finance)The restricted shares with a market value of 2.546 billion yuan were lifted today. Yongda, Sitaili and Dameng Data were among the top companies in terms of market value. On Thursday (December 12), the restricted shares of 8 companies were lifted, with a total lifting amount of 175 million shares. According to the latest closing price, the total lifting market value was 2.546 billion yuan. Judging from the amount of lifting the ban, the number of shares lifted by the two companies exceeded 10 million. Si Taili, Yongda and Ningxin New Materials were among the top, with 95,895,400 shares, 65,203,300 shares and 6,633,200 shares respectively. Judging from the market value of lifting the ban, the number of shares lifted by the two companies exceeded 100 million yuan. Yongda Co., Ltd., Sitaili and Dameng Data are among the top companies in terms of market value, with market values of 1.039 billion yuan, 992 million yuan and 349 million yuan respectively. Judging from the proportion of shares released from the ban to the total share capital, the proportion of the two companies released from the ban exceeded 10%. Yongda Co., Ltd., Sitaili Co., Ltd. and Ningxincai Co., Ltd. have the highest proportion of lifting the ban, accounting for 27.17%, 21.87% and 7.13% respectively.

Zhong Xuegao's subsidiary was forced to execute 16.62 million yuan. According to the legal litigation information, recently, Zhongmao (Shanghai) Food Technology Co., Ltd. added a piece of information about the person to be executed, with the execution target of 16.62 million yuan. The enforcement court is the Yangpu District People's Court in Shanghai. Zhongmao (Shanghai) Food Technology Co., Ltd. was established in June 2020. The legal representative is Wang Keqin, with a registered capital of RMB 10 million, and it is wholly owned by Zhong Xuegao Food (Shanghai) Co., Ltd. Tianyan risk information shows that the company has more than 20 pieces of information about executed persons, and the total amount of execution exceeds 31.62 million yuan. In addition, there are also a number of consumption restriction orders, untrustworthy executed persons (Lao Lai) and final case information.South Korean President Yin Xiyue appeared in the office on Thursday for the first time in five days.Google executives: Search for artificial intelligence is the biggest bet, with an estimated investment of 50 billion yuan in 2024. ruth porat, president and chief investment officer of Google, revealed at a conference that Google's biggest bet is to apply artificial intelligence to search business. Despite the problems of technical competition and artificial intelligence model, Google is still firmly pushing forward this strategy. Polat emphasized that integrating artificial intelligence into search business is Google's current core strategy. Google has introduced an overview of AI into the search tool, added advertisements to it, and introduced shopping advertisements to Google Lens. Despite the existence of false or misleading results such as artificial intelligence illusion, Google is still optimistic about the development potential of artificial intelligence in the search field. In addition to the search business, Polat also pointed out that Google Cloud is another important investment of the company. When answering a question about whether Google's investment cost in artificial intelligence will follow the industry trend, Polat said that artificial intelligence represents "an opportunity for generations". She revealed that Google plans to spend $50 billion on chips, data centers and other capital expenditures in 2024, but stressed that Google will make careful bets based on the results.

Australia's 3-year government bond yield increased, and Australia's unemployment rate decreased.South Korean President Yin Xiyue: The opposition party is trying to destroy South Korea's growth engine.Syrian Human Rights Watch: Israel continues to air strike Syrian military facilities. On the 12th local time, Syrian Human Rights Watch said that Israeli warplanes continued to launch air strikes against military facilities in Syria, including military sites in Latakia port and arsenals in Tartus province. According to the organization, this is the fourth consecutive day that Israeli warplanes launched an air strike on the Syrian arsenal after the overthrow of Bashar al-Assad's government.